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Graduate Mentors

Our Graduate Mentors are former students in SPS who are currently enrolled in a graduate programme in NUS

CHEMISTRY

  john_ouyang Ouyang Fengcong, John 

Current Research

  • Distributed multipole analysis (Computational chemistry)

Past Research

  • Solvation free energies of amino acids using the cluster continuum model (Computational chemistry)
  • Monomer synthesis of telomerase-inhibiting ligand for binding to telomeric RNA g-quadruplex (Chemical biology)
  • Literature review on dye sensitised solar cells

Academic Interest

  • Computational chemistry: Distributed multipoles, solvation studies
  • Keen on writing programs for comp chem using Fortran
  • Would not mind venturing into physical chemistry or inorganic chemistry as well

 

COMPUTATIONAL BIOLOGY

  weiwei Luo Weiwei 

Specialisation: Computational biology 

Current Research

  • Self-organization of actin network through actomyosin contractility, formin-driven actin polymerization, and filamin-mediated cross-linking

Past Research

  • Environmental sensing and motility of hMSC cells on three dimensional nanotopography
  • Computer aided model of survival pathways in LNCaP cells
  • Cross-talks in Apoptosis: perspective in cancer study
  • Heat Shock Effect on Angiogenesis
  • Neuron Induction in Embryonic Stem Cell
  • Understanding the psychological effects of power and status on people in interactions: data mining

Academic Interest

  • Cytoskeleton generates coordinated forces that enable the cell to move and change shape. I am interested in the study of actin cytoskeletal mechanics, and working to identify, measure, and describe how the forces for motility and morphogenesis are expressed at the molecular and cellular level. I am experienced in cytoskeleton dynamics and mechanobiology; familiar with the technologies such as micro-fabrication, advanced cellular imaging (Confocal, TIRF, PALM&STORM) and imaging data analysis; with some experience of Fluorescence correlation spectroscopy and Cryo-electron microscopy and tomography
  • Mechanobiology: the study of molecular, cellular and tissue mechanics
  • Working to identify, measure, and describe how the forces for motility and morphogenesis are expressed at the tissue, molecular and cellular level
    • Cell migration and actin cytoskeleton
    • Cell adhesion to extracellular matrix and other cells
    • Microtubules and molecular motors
    • Signaling in cell mechanosensing, polarization and migration
    • Computational biology: computational modelling of cell signalling pathways
  qin_chu Qin Chu 

Specialisation: Computational biology 

Current Research

  • Biomarker discovery
  • Bioinformatics database
  • System level multi-target drug discovery

Past Research

  • Bioprospecting
  • In silico drug design
  • Microarray primer design
  • Computational neuroscience

Academic Interest

  • Computer-aided drug design
  • Personalized medicine
  • Computational biology
  • Bioinformatics
  liu_xuan_yao Liu Xuan Yao 

Specialisation: Computational biology (Molecular epidemiology) 

Current Research

  • Developing new method for identifying very recent positive selection across human genome

Past Research

  • Motif module discovery using chip-seq of transcription factors in correlation with gene expression: a breast cancer case study

Academic Interest

  • Computational genomics
  • Molecular epidemiology

 

LIFE SCIENCES

  daphne_ng Daphne Ng Hui Ping 

Specialisation: Microbiology

Current Research

  • Use of the halotolerant microalga Dunaliella in carbon dioxide sequestration/capture
  • Production of biomolecules from photosynthetic microalgae
  • Genetic engineering of microalgae

Past research

  • Pathogenesis of the rice blast fungus Magnaporthe grisea
  • Production of biofuel from microalgae

Academic Interest

  • Microbiology and biotechnology
  daphne_wong Daphne Wong Pei Wen 

Specialization: Biochemistry 

Current Research

  • Regulation of histone demethylases leading to altered gene expression and tumour progression (Epigenetics and cancer)

Past Research

  • Metastasis and cancer
  • Effect of collagen inhibitors in angiogenesis in zebrafish models

Academic Interest

  • Cancer, protein stability and ubiquitination, drug discovery, pharmacology, epigenetics

Publications

  • DP Wong, G Wells, T Hagen. Heteroaromatic 4-arylquinols are novel inducers of Nuclear factor-erythroid 2-related factor 2 (Nrf2). Eur J. Pharmacol. 643:188-94 (2010)
  • DP Wong, G Wells, T Hagen.The Induction of Phase 2 Response in Chemoprevention by Heteraromatic Quinols. 15th (NUROP) National Undergraduate Research Opportunities Programme Congress (2010)
  dong_di Dong Di 

Specialization: Integrated biology and medicine 

Current Research

  • Health economics and health services

Past Research

  • Mitochondria dysfunction and Parkinson’s disease (neuroscience)
  • Apoptosis during neuronal development
  • Histone variants in embryonic stem cell differentiation (epigenetics)
  • Ex vivo expansion and in vivo reconstitution of hematopoietic stem cells (stem cell, immunology)

Academic Interest

  • Health economics, stem cells, epigenetics, immunology, neuron science and behavioral studies
  ives_lim Ives Lim Yubin 

Specialisation: Molecular cell biology 

Current Research

  • Developmental origins of health and disease (DOHaD)
  • DNA Methylation studies
  • Gestational Diabetes
  • http://devos.sg/teamDevOS/postgraduate.html#ives

Past Research

  • Cancer angiogenesis
  • Zebrafish embryogenesis
  • Gastric cancer proteomics
  • Influence of microbiota on the epigenetics of gut

Academic Interest

  • Ecological biogeography and marine biology
  lee_yew_mun Lee Yew Mun 

Specialisation: Molecular cell biology 

Current Research

  • Proteomic analysis of molecular signalling pathways involved in the protection of the myocardium from ischemic-reperfusion injury by postconditioning in an in vitro model

Past Research

  • Studying the roles of a novel protein, Aph2, in DNA damage signalling pathways
  • Roles of saturated fatty acids in DNA damage signalling pathways

Academic Interest

  • Molecular and Cell Biology:
    • Understanding and elucidating protein signalling pathways which are important for the proper development of an organism
    • Identifying cellular survival cascades that are activated by respective treatments to protect the cell from further injuries which lead to cell death
    • DNA damage signaling cascade and DNA repair mechanisms
    • Autophagic progresses of the cell
    • Functions of miRNA in the proper development of an organism
  lester-lin Lin Bocheng Lester

Specialisation: Molecular and Cell Biology 

Current Research

  • Coupling of biochemistry & force-sensing in regulation of tissue growth
  • Representation & analysis of biological information on algebraic and graph structures

Past Research

  • Hippo-YAP signaling (Biochemistry, Imaging)

Academic Interests
Experiments, informatics, simulation & theories relating to:

  • Protein/Genetic/Metabolic networks
  • Cellular & tissue mechanics
  • Algebra & Graph theory
  png-yi-tian Png Yi Tian

Specialisation: Molecular and Cell Biology 

Current Research

  • Investigating the cytolytic activity of expanded and activated allogenic human natural killer (NK) cells on advanced leukemia/solid tumor

Past Research

  • (SP2172) BH3 mimetics, ABT-737 and GX015-070, work synergistically to induce cell death in leukaemic cell lines
  • (SP2171) Biomarker Discovery for the Enhancement of Acute Lymphoblastic Leukaemia Diagnosis
  • Developing a human Embryonic Stem Cells (hESC)-based cellular assay for high-throughput developmental toxicity screening

Academic Interests

  • Immunology (Tumour Immunology, NK cells), Stem Cells Biology and Applications, Apoptosis
  rachel_oh Rachel Oh Rui Ying 

Specialisation: Environmental biology 

Past Research

  • Proteomic analysis of molecular signaling pathways involved in the protection of the myocardium from ischemic-reperfusion injury by postconditioning using an in vitro model
  • Elucidating factors affecting sedimentation in mangroves
  • The influence of biotic and abiotic factors of the distribution of tree seedlings on Tutuila Island, American Samoa
  • Ecological Mangrove Restoration — with focus on geomorphology and mangrove forest restoration/rehabilitation

Academic Interest

  • Environmental Sciences
  • Geosciences
  • Issues that involve interdisciplinary studies – particularly the physical environmental and its effects on ecological/biological issues
  tan_kai_sen Tan Kai Sen 

Specialisation: Infectious diseases 

Current Research

  • Influenza virus and therapy research beased on host factors
  • miRNA base tissue repair of injured lungs

Past Research

  • Exploring novel treatments for influenza infection
  • in vitro and in vivo activities of visperin in influenza infection

Academic Interest

  • Host factors as a component for antiviral therapy
  • Regenerative medicine
  • Small RNAs (miRNAs and siRNAs) and their physiologival role in viral diseases
  • Gene therapy, DNA vaccines and in vivo plasmid/vector therapy models for viral diseases
  • Virology and infectious diseases
  • Stem cell biology

 

PHYSICS

  yang_tzyh_haur Yang Tzyh Haur 

Current Research

  • Quantum nonlocality and thermodynamics

Academic Interest

  • Quantum mechanics- Entanglement, teleportation, decoherence , no cloning theorem, quantum-classical correspondence
  • Group theory and symmetry in physics
  le_phuc_thinh Le Phuc Thinh 

Current Research

  • Quantum Cryptography (reference frame independent protocol with higher dimensional coding)

Academic Interest

  • Nonlocality (quantum set and Bell’s inequality)
  • Quantum information in general
  cai_yu Cai Yu 

Current Research

  • Quantum Bell’s inequality (CGLMP), polytope and dimension witness

Academic Interest

  • General physics especially quantum mechanics
  • Crytography
  han_weiding Han Weiding 

Current Research

  • Radial Mirror Analyzers in Scanning Electron Microscopes (ECE)

Past Research

  • An Investigation of the existence of closed timelike curves and the feasibility of time travel
  • Making sense of time travel paradoxes in van Stockum space-time
  • Ising model in teaching-learning processes
  • HBT effect in thermal light sources

Academic Interest

  • Particle physics
  • General relativity
  • Electron optics
  • Computational Physics
  tang_zhongkan Tang Zhongkan Kamiyuki 

Current Research

  • Polarization-entangled photon pairs on satellite system (Experimental)

Past Research

  • SP2171:The definition of a second and the atomic clock (Literature review)
  • PC3180: Mode-locking laser and Frequency comb (Literature review)
  • SP2172: Stellar interferometer using Hanbury Brown and Twiss (HBT) Effect (Experimental)
  • UROPS: Quantum teleportation using three-particle entanglement in non-inertia frame (Theoretical)
  • ISM: Advanced General Relativity (Theoretical)
  • FYP: Quantum Revival in open systems (Theoretical + Computational)
  siu-zhou-bin Siu Zhuo Bin 

Current Research

  • Spin and charge transport in nanostructures

Academic Interest

  • Computational physics
  • Condensed matter physics 
  • Nanoscience and nanotechnology
  sawthuanbeng Saw Thuan Beng

Current Research

  • Biomechanics (cell-cell junction, start from Aug 2012)

Past Research

  • Biomechanics (inflammation, atherosclerosis and stents) (2010 – 2012)
  • Quantum information (preserve coherence of entangled qubits)(2008-2010)

Academic Interest

  • Biomechanics/biophysics
  • Biology in general
  • Macrophysics (in particular soft matter)
  • Other physics (but not mathematical or computational physics)
  seah-wei-ling Seah Wei Ling

Current Research

  • Polymer light-emitting diodes: preparation and investigation of device performance and efficiency during operation

Past Research

  • Use of a scanning mirror on vibrating membrane to create a dynamic optical trap
  • Synthesis and characterization of gold nanotubes
  • Investigation of work function of organic polymers to facilitate hole-injection in polymer light-emitting diodes

Academic Interests

  • Organic Electronics
  • Material Science/Nanoscience
  • Surface Physics